Talk:Uniparental disomy

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In the third paragraph, it currently states: "However, if the UPD causing event happens during meiosis I, the genotype may include identical copies of the uniparental chromosome (isodisomy), leading to the manifestation of rare recessive disorders." I'm pretty sure this is only likely to occur if the UPD causing event occurs in meiosis II, when the sister chromatids separate. I will change it. If I am wrong, comment here and then change it back.

Dwinetsk 09:12, 13 November 2007 (UTC)

When the child receives the (two) homologous chromosomes (inherited from both grandparents) from one parent, this is called an heterodisomic UPD. I'm confused. The way this is worded, it sounds like that would mean that the child would inherit all of, say, his father's chromosomes, and none of his mother's. Would that make the child, in effect, a clone of his father? Nik42 (talk) 01:32, 30 April 2008 (UTC)

Never mind. I figured it out. It's only one pair of chromosomes involved, not all 23 ... but that would mean that the child would be more closely related to one parent than the other, yes? Nik42 (talk) 01:34, 30 April 2008 (UTC)