ULK1

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Unc-51-like kinase 1 (C. elegans)
Identifiers
Symbol(s) ULK1; ATG1; FLJ38455; UNC51; Unc51.1
External IDs OMIM: 603168 MGI1270126 HomoloGene2640
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 8408 22241
Ensembl ENSG00000177169 n/a
Uniprot O75385 n/a
Refseq XM_001133335 (mRNA)
XP_001133335 (protein)
XM_990757 (mRNA)
XP_995851 (protein)
Location Chr 12: 130.95 - 130.97 Mb n/a
Pubmed search [1] [2]

Unc-51-like kinase 1 (C. elegans), also known as ULK1, is a human gene.[1]


[edit] References

[edit] Further reading

  • Kuroyanagi H, Yan J, Seki N, et al. (1998). "Human ULK1, a novel serine/threonine kinase related to UNC-51 kinase of Caenorhabditis elegans: cDNA cloning, expression, and chromosomal assignment.". Genomics 51 (1): 76–85. PMID 9693035. 
  • Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (5): 277–86. PMID 9872452. 
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863. 
  • Okazaki N, Yan J, Yuasa S, et al. (2001). "Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation.". Brain Res. Mol. Brain Res. 85 (1-2): 1–12. PMID 11146101. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Tomoda T, Kim JH, Zhan C, Hatten ME (2004). "Role of Unc51.1 and its binding partners in CNS axon outgrowth.". Genes Dev. 18 (5): 541–58. doi:10.1101/gad.1151204. PMID 15014045. 
  • Young AR, Chan EY, Hu XW, et al. (2006). "Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes.". J. Cell. Sci. 119 (Pt 18): 3888–900. doi:10.1242/jcs.03172. PMID 16940348. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Wissing J, Jänsch L, Nimtz M, et al. (2007). "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.". Mol. Cell Proteomics 6 (3): 537–47. doi:10.1074/mcp.T600062-MCP200. PMID 17192257. 
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
  • Chan EY, Kir S, Tooze SA (2007). "siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy.". J. Biol. Chem. 282 (35): 25464–74. doi:10.1074/jbc.M703663200. PMID 17595159.