UDP-glucose-glycoprotein glucose phosphotransferase

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In enzymology, an UDP-glucose-glycoprotein glucose phosphotransferase (EC 2.7.8.19) is an enzyme that catalyzes the chemical reaction

UDP-glucose + glycoprotein D-mannose UMP + glycoprotein 6-(D-glucose-1-phospho)-D-mannose

Thus, the two substrates of this enzyme are UDP-glucose and glycoprotein D-mannose, whereas its two products are UMP and glycoprotein 6-(D-glucose-1-phospho)-D-mannose.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is UDP-glucose:glycoprotein-D-mannose glucosephosphotransferase. Other names in common use include UDP-glucose:glycoprotein glucose-1-phosphotransferase, GlcPTase, Glc-phosphotransferase, and uridine diphosphoglucose-glycoprotein glucose-1-phosphotransferase.

[edit] References

• IUBMB entry for 2.7.8.19
• BRENDA references for 2.7.8.19 (Recommended.)
• PubMed references for 2.7.8.19
• PubMed Central references for 2.7.8.19
• Google Scholar references for 2.7.8.19
• Koro LA, Marchase RB (1982). "A UDP-glucose:glycoprotein glucose-1-phosphotransferase in embryonic chicken neural retina". Cell. 31: 739–48. doi:10.1016/0092-8674(82)90328-2. PMID 6297779. 

[edit] External links

The CAS registry number for this enzyme class is 84861-40-5.

• IUBMB entry for 2.7.8.19

• KEGG entry for 2.7.8.19

• BRENDA entry for 2.7.8.19

• NiceZyme view of 2.7.8.19

• EC2PDB: PDB structures for 2.7.8.19

• PRIAM entry for 2.7.8.19

• PUMA2 entry for 2.7.8.19

• IntEnz: Integrated Enzyme entry for 2.7.8.19

• MetaCyc entry for 2.7.8.19

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047358: UDP-glucose-glycoprotein glucose phosphotransferase

• AMIGO entry for GO code 0047358: UDP-glucose-glycoprotein glucose phosphotransferase