UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase
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In enzymology, an UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase (EC 2.6.1.34) is an enzyme that catalyzes the chemical reaction
- UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose + 2-oxoglutarate UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose + L-glutamate
Thus, the two substrates of this enzyme are UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose and 2-oxoglutarate, whereas its two products are UDP-2-acetamido-4-dehydro-2,6-dideoxyglucose and L-glutamate.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose:2-oxoglutarate aminotransferase. Other names in common use include uridine diphospho-4-amino-2-acetamido-2,4,6-trideoxyglucose, and aminotransferase. It employs one cofactor, pyridoxal phosphate.
[edit] References
- IUBMB entry for 2.6.1.34
- BRENDA references for 2.6.1.34 (Recommended.)
- PubMed references for 2.6.1.34
- PubMed Central references for 2.6.1.34
- Google Scholar references for 2.6.1.34
- Distler J, Kaufman B, Roseman S (1966). "Enzymic synthesis of a diamino sugar nucleotide by extracts of type XIV Diplococcus pneumoniae". Arch. Biochem. Biophys. 116: 466–78. doi: . PMID 4381351.
[edit] External links
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- The CAS registry number for this enzyme class is 37277-89-7.