U6 spliceosomal RNA

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U6 spliceosomal RNA

Type:	Gene; snRNA; splicing;
2° structure:	Published; PubMed; Griffiths-Jones SR
Seed alignment:	Griffiths-Jones SR
Avg length:	105.7 nucleotides
Avg identity:	77%

U6 snRNA is a non-coding RNA that is a component of the spliceosome which is involved in splicing pre-mRNA. The putative secondary structure consensus base pairing is confined to a short 5' stem-loop, but U6 snRNA is thought to form extensive base-pair interactions with U4 snRNA.^[1] There appear to be many copies of U6 derived pseudogenes or repeats in vertebrate genomes.

[edit] References

^ Orum, H; Nielsen H, Engberg J (1991). "Spliceosomal small nuclear RNAs of Tetrahymena thermophila and some possible snRNA-snRNA base-pairing interactions". J Mol Biol 222: 219–232. doi:10.1016/0022-2836(91)90208-N. PMID 1960724.

Zwieb, C (1997). "The uRNA database". Nucleic Acids Res 25: 102–103. doi:10.1093/nar/25.1.102. PMID 9016512.
Thomas, J; Lea K, Zucker-Aprison E, Blumenthal T (1990). "The spliceosomal snRNAs of Caenorhabditis elegans". Nucleic Acids Res 18: 2633–2642. doi:10.1093/nar/18.9.2633. PMID 2339054.