Tyrosine 2,3-aminomutase

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In enzymology, a tyrosine 2,3-aminomutase (EC 5.4.3.6) is an enzyme that catalyzes the chemical reaction

L-tyrosine 3-amino-3-(4-hydroxyphenyl)propanoate

Hence, this enzyme has one substrate, L-tyrosine, and one product, 3-amino-3-(4-hydroxyphenyl)propanoate.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring amino groups. The systematic name of this enzyme class is L-tyrosine 2,3-aminomutase. This enzyme is also called tyrosine alpha,beta-mutase. This enzyme participates in tyrosine metabolism. It employs one cofactor, ATP.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2OHY.

[edit] References

• IUBMB entry for 5.4.3.6
• BRENDA references for 5.4.3.6 (Recommended.)
• PubMed references for 5.4.3.6
• PubMed Central references for 5.4.3.6
• Google Scholar references for 5.4.3.6
• Kurylo-Borowska Z, Abramsky T (1972). "Biosynthesis of -tyrosine". Biochim. Biophys. Acta. 264: 1–10. PMID 5021987. 

[edit] External links

The CAS registry number for this enzyme class is 9073-38-5.

• IUBMB entry for 5.4.3.6

• KEGG entry for 5.4.3.6

• BRENDA entry for 5.4.3.6

• NiceZyme view of 5.4.3.6

• EC2PDB: PDB structures for 5.4.3.6

• PRIAM entry for 5.4.3.6

• PUMA2 entry for 5.4.3.6

• IntEnz: Integrated Enzyme entry for 5.4.3.6

• MetaCyc entry for 5.4.3.6

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050368: tyrosine 2,3-aminomutase

• AMIGO entry for GO code 0050368: tyrosine 2,3-aminomutase