Talk:Tyrosine
From Wikipedia, the free encyclopedia
 |
Tyrosine is within the scope of WikiProject Chemicals, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project. | ||
 |
This article is also supported by WikiProject Chemistry. | ||
| Core | This is a core article in the WikiProject Chemicals worklist. | ||
| Start | This article has been rated as Start-Class on the quality scale. | ||
| Mid | This article has been rated as mid-importance on the importance scale. | ||
|
Article Grading: The article has been rated for quality and/or importance but has no comments yet. If appropriate, please review the article and then leave comments here to identify the strengths and weaknesses of the article and what work it will need. |
|||
 |
This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The WikiProject's current monthly collaboration is focused on improving Restriction enzyme. |
||
| Start | This article has been rated as Start-Class on the assessment scale. |
||
| High | This article is on a subject of High-importance within molecular and cellular biology. | ||
|
Article Grading: The article has been rated for quality and/or importance but has no comments yet. If appropriate, please review the article and then leave comments here to identify the strengths and weaknesses of the article and what work it will need. |
|||
Contents |
[edit] Questions
Has anyone ever tried or heard of using tyrosine to help darken the mouth pigment in dogs?
Does tyrosine accumulate in the body (organs) or is it water soluble?
[edit] metabolism?
It'd be nice to see some more information on the metabolic effects in humans. I see this is included in certain energy drinks, so it would be good to know it's effect. The current article has little detail.
You can enhance your vigilance a little bit, if you swallow l-tyrosine pills. 500-1000 g are the right dose. Tyrosine is changing in adrenalin and melanin. Also it gets metabolize in hormones for the gland of thyroid. Your blood.pressure gets enhanced! --Fackel 20:47, 30 May 2006 (UTC)
-->I think you mean 500 - 1000 milligrams
--> lol, yeah we may have lost a couple of the more trusting wikiers due to that mistake...
[edit] Medical Usage
What medical uses are there for tyrosine? I also read that it can promote the division of cancer cells, especially malignant melanoma.
- Not really... since it's an essential amino acid it is absolutely required by the human body. You might be talking about tyrosine kinases, enzymes that make the tyrosine phosphorylated (adds a phosporus). That would be a good article to link to from here. --Antorjal 05:00, 5 September 2006 (UTC)
[edit] Enzymatic hydroxylation to give m- and o- isomers??
The current graphic has something about "enzymatic" hydroxylation to give ortho- and meta-isomers. I dont know of any evidence for this hydroxylation being directed by enzymatic processes vs some normal free radical degradation. So I am questioning the validity of the graphic.--Smokefoot 22:21, 22 October 2007 (UTC)
- I just updated the graphic based on the previous version. Perhaps the graphic is not as clear as it should be, but it should be interpreted as enzymatic oxidation leading only to the para isomer (this needs to be verified) whereas free radical oxidation (represented by HO.) leads to ortho and meta (as well as para). Boghog2 22:26, 22 October 2007 (UTC)
-
- I revised the figure to make it clearer that enzymatic oxidation by phenylalanine hydroxylase only refers to the top reaction. The second and third arrows refer to free radical oxidation. I hope this eliminates the confusion. Cheers. Boghog2 06:54, 23 October 2007 (UTC)
[edit] daily dose?
Suggests (without citation) 100mg/kg per day, then says this is equivalent to 500-1500mg per day. So the average adult wieghs between 5kg and 15kg? Either a typo in the dose or in multiplying the dose up for the daily amount. Also, since it claims that the dose/kg is supported by literature this shouldnt be included without a citation.172.201.254.138 11:37, 1 December 2007 (UTC)
- The 500-1500mg per day is the dosage suggested by manufacturers. The dosage of 100mg/kg per day appears in clinical studies. I added citation of clinical study to treat depression with tyrosine where that dosage was used.--Nawojka (talk) 12:41, 26 March 2008 (UTC)
[edit] Cocaine and Tyrosine?
I have recently added a line about Cocaine and Tyrosine, suggesting that taking Tyrosine after using Cocaine can reduce the "hangover" and depression effects associated with Cocaine usage This addition was deleted, and I am not sure why I have seen it used many times and produce positive results
I believe that this is an important piece of information, and that it is relevant, I was wondering if anybody objects that I will add it again?
it is a problem to talk about Drugs?
Cocaine stimulate the creation of Dopamine. and Dopamine creation uses tyrosine, and the body has limited ability to create tyrosine. Most Cocaine users don't eat regularly, and as a result lack the Tyrosine. user:Vishvash —Preceding comment was added at 00:20, 16 January 2008 (UTC)
Would it be useful in helping people to withraw from and stop using cocaine if they are addicted? —Preceding unsigned comment added by 69.120.107.230 (talk) 05:05, 28 January 2008 (UTC)
