TXNL1

From Wikipedia, the free encyclopedia

Thioredoxin-like 1

PDB rendering based on 1gh2.

Available structures: 1gh2, 1wwy

Identifiers

Symbol(s)

TXNL1; TRP32; TXL-1; TXNL; Txl

External IDs

OMIM: 603049 MGI: 1860078 HomoloGene: 3515

Gene ontology
Molecular Function:	• electron carrier activity • protein disulfide oxidoreductase activity • thiol-disulfide exchange intermediate activity
Cellular Component:	• cytoplasm
Biological Process:	• electron transport • transport • apoptosis • signal transduction • cell redox homeostasis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_004786 (mRNA)
NP_004777 (protein)

NM_016792 (mRNA)
NP_058072 (protein)

Location

Chr 18: 52.42 - 52.47 Mb

Chr 18: 63.79 - 63.82 Mb

Pubmed search

[1]

[2]

Thioredoxin-like 1, also known as TXNL1, is a human gene.^[1]

[edit] References

^ Entrez Gene: TXNL1 thioredoxin-like 1.

[edit] Further reading

Miranda-Vizuete A, Gustafsson JA, Spyrou G (1998). "Molecular cloning and expression of a cDNA encoding a human thioredoxin-like protein.". Biochem. Biophys. Res. Commun. 243 (1): 284-8. doi:10.1006/bbrc.1997.8003. PMID 9473519.
Lee KK, Murakawa M, Takahashi S, et al. (1998). "Purification, molecular cloning, and characterization of TRP32, a novel thioredoxin-related mammalian protein of 32 kDa.". J. Biol. Chem. 273 (30): 19160-6. PMID 9668102.
Miranda-Vizuete A, Spyrou G (2000). "Genomic structure and chromosomal localization of human thioredoxin-like protein gene (txl).". DNA Seq. 10 (6): 419-24. PMID 10826702.
Jin J, Chen X, Zhou Y, et al. (2002). "Crystal structure of the catalytic domain of a human thioredoxin-like protein.". Eur. J. Biochem. 269 (8): 2060-8. PMID 11985582.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.". Nat. Biotechnol. 21 (5): 566-9. doi:10.1038/nbt810. PMID 12665801.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Kim KY, Lee JW, Park MS, et al. (2006). "Expression of a thioredoxin-related protein-1 is induced by prostaglandin E(2).". Int. J. Cancer 118 (7): 1670-9. doi:10.1002/ijc.21572. PMID 16231315.
Guo D, Han J, Adam BL, et al. (2005). "Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress.". Biochem. Biophys. Res. Commun. 337 (4): 1308-18. doi:10.1016/j.bbrc.2005.09.191. PMID 16236267.
Jiménez A, Pelto-Huikko M, Gustafsson JA, Miranda-Vizuete A (2006). "Characterization of human thioredoxin-like-1: potential involvement in the cellular response against glucose deprivation.". FEBS Lett. 580 (3): 960-7. doi:10.1016/j.febslet.2006.01.025. PMID 16438969.