Twinrix

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Twinrix is a vaccine against hepatitis A and hepatitis B. Twinrix is administered over three doses.

The name was created because it is a mixture of two earlier vaccines - Havrix, an inactivated-virus Hepatitis A vaccine, and ENGERIX-B, a recombinant Hepatitis B vaccine.

The CDC reports that clinical trials found the following levels of protection against Hep A and Hep B one month after each dose[1]:
A: 93.8% 98.8% 99.9%
B: 30.8% 78.2% 98.5% GlaxoSmithKline claims that its studies found 70% of subjects had antibodies against hepatitis B a month after just the first dose, however.[2]

TWINRIX, HAVRIX and ENGERIX-B are registered trademarks of GlaxoSmithKline; if the same vaccine is available from others, it will have another name.

[edit] References

  1. ^ Notice to Readers: FDA Approval for a Combined Hepatitis A and B Vaccine
  2. ^ Twinrix Adult Vaccine , SPC from the eMC

[edit] External links

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