TWF2

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Twinfilin, actin-binding protein, homolog 2 (Drosophila)
Identifiers
Symbol(s) TWF2; A6RP; A6r; MSTP011; PTK9L
External IDs OMIM: 607433 MGI: 1346078 HomoloGene: 5272
Orthologs
Human Mouse
Entrez 11344 23999
Ensembl n/a ENSMUSG00000023277
Uniprot n/a Q9Z0P5
Refseq NM_007284 (mRNA)
NP_009215 (protein)		 NM_011876 (mRNA)
NP_036006 (protein)
Location n/a Chr 9: 106.06 - 106.07 Mb
Pubmed search [1] [2]

Twinfilin, actin-binding protein, homolog 2 (Drosophila), also known as TWF2, is a human gene.[1]

The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein.[1]

[edit] References

  1. ^ a b Entrez Gene: TWF2 twinfilin, actin-binding protein, homolog 2 (Drosophila).

[edit] Further reading

  • Yamada S, Uchimura E, Ueda T, et al. (2007). "Identification of twinfilin-2 as a factor involved in neurite outgrowth by RNAi-based screen.". Biochem. Biophys. Res. Commun. 363 (4): 926-30. doi:10.1016/j.bbrc.2007.09.069. PMID 17910947. 
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
  • Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.". Nat. Biotechnol. 23 (1): 94-101. doi:10.1038/nbt1046. PMID 15592455. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Vartiainen MK, Sarkkinen EM, Matilainen T, et al. (2003). "Mammals have two twinfilin isoforms whose subcellular localizations and tissue distributions are differentially regulated.". J. Biol. Chem. 278 (36): 34347-55. doi:10.1074/jbc.M303642200. PMID 12807912. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422-35. doi:10.1101/gr.154701. PMID 11230166. 
  • Rohwer A, Kittstein W, Marks F, Gschwendt M (1999). "Cloning, expression and characterization of an A6-related protein.". Eur. J. Biochem. 263 (2): 518-25. PMID 10406962. 
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