TUSC4

From Wikipedia, the free encyclopedia


Tumor suppressor candidate 4
Identifiers
Symbol(s) TUSC4; NPR2L; NPRL2
External IDs OMIM: 607072 MGI1914482 HomoloGene4771
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 10641 56032
Ensembl ENSG00000114388 ENSMUSG00000010057
Uniprot Q8WTW4 Q9WUE4
Refseq NM_006545 (mRNA)
NP_006536 (protein)
XM_978349 (mRNA)
XP_983443 (protein)
Location Chr 3: 50.36 - 50.36 Mb Chr 9: 107.4 - 107.4 Mb
Pubmed search [1] [2]

Tumor suppressor candidate 4, also known as TUSC4, is a human gene.[1]


[edit] References

[edit] Further reading

  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
  • Ueda K, Kawashima H, Ohtani S, et al. (2007). "The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells.". Cancer Res. 66 (19): 9682–90. doi:10.1158/0008-5472.CAN-06-1483. PMID 17018626. 
  • Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3.". Nature 440 (7088): 1194–8. doi:10.1038/nature04728. PMID 16641997. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Li J, Wang F, Haraldson K, et al. (2004). "Functional characterization of the candidate tumor suppressor gene NPRL2/G21 located in 3p21.3C.". Cancer Res. 64 (18): 6438–43. doi:10.1158/0008-5472.CAN-03-3869. PMID 15374952. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ji L, Nishizaki M, Gao B, et al. (2002). "Expression of several genes in the human chromosome 3p21.3 homozygous deletion region by an adenovirus vector results in tumor suppressor activities in vitro and in vivo.". Cancer Res. 62 (9): 2715–20. PMID 11980673. 
  • Lerman MI, Minna JD (2000). "The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.". Cancer Res. 60 (21): 6116–33. PMID 11085536.