TSFM

From Wikipedia, the free encyclopedia

Ts translation elongation factor, mitochondrial

PDB rendering based on 2cp9.

Available structures: 2cp9

Identifiers

Symbol(s)

TSFM; COXPD3; EF-TS; EF-Tsmt

External IDs

OMIM: 604723 MGI: 1913649 HomoloGene: 4184

Gene ontology
Molecular Function:	• transcription elongation regulator activity • translation elongation factor activity
Cellular Component:	• intracellular • mitochondrion
Biological Process:	• translational elongation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_005726 (mRNA)
NP_005717 (protein)

NM_025537 (mRNA)
NP_079813 (protein)

Location

Chr 12: 56.46 - 56.48 Mb

Chr 10: 126.43 - 126.43 Mb

Pubmed search

[1]

[2]

Ts translation elongation factor, mitochondrial, also known as TSFM, is a human gene.^[1]

[edit] References

^ Entrez Gene: TSFM Ts translation elongation factor, mitochondrial.

[edit] Further reading

Smeitink JA, Elpeleg O, Antonicka H, et al. (2006). "Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs.". Am. J. Hum. Genet. 79 (5): 869-77. doi:10.1086/508434. PMID 17033963.
Antonicka H, Sasarman F, Kennaway NG, Shoubridge EA (2006). "The molecular basis for tissue specificity of the oxidative phosphorylation deficiencies in patients with mutations in the mitochondrial translation factor EFG1.". Hum. Mol. Genet. 15 (11): 1835-46. doi:10.1093/hmg/ddl106. PMID 16632485.
Maksimov VV, Arman IP, Tarantul VZ (2006). "[Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system]". Genetika 42 (2): 274-7. PMID 16583711.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Vernon JL, Burr PC, Wiley JE, Farwell MA (2000). "Assignment of the mitochondrial translation elongation factor Ts gene (TSFM) to human chromosome 12 bands q13-->q14 by in situ hybridization and with somatic cell hybrids.". Cytogenet. Cell Genet. 89 (3-4): 145-6. PMID 10965106.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548.
Benkowski LA, Takemoto C, Ott G, et al. (1996). "Interaction of mitochondrial elongation factors Tu.Ts with aminoacyl-tRNA.". Nucleic Acids Symp. Ser. (33): 163-6. PMID 8643359.
Xin H, Woriax V, Burkhart W, Spremulli LL (1995). "Cloning and expression of mitochondrial translational elongation factor Ts from bovine and human liver.". J. Biol. Chem. 270 (29): 17243-9. PMID 7615523.