Tryptophanamidase

From Wikipedia, the free encyclopedia

In enzymology, a tryptophanamidase (EC 3.5.1.57) is an enzyme that catalyzes the chemical reaction

L-tryptophanamide + H₂O L-tryptophan + NH₃

Thus, the two substrates of this enzyme are L-tryptophanamide and H₂O, whereas its two products are L-tryptophan and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is L-tryptophanamide amidohydrolase. Other names in common use include tryptophan aminopeptidase, and L-tryptophan aminopeptidase. It employs one cofactor, manganese.

[edit] References

• IUBMB entry for 3.5.1.57
• BRENDA references for 3.5.1.57 (Recommended.)
• PubMed references for 3.5.1.57
• PubMed Central references for 3.5.1.57
• Google Scholar references for 3.5.1.57
• Iwayama A, Kimura T, Adachi O and Ameyama M (1983). "Crystallization and characterization of a novel aminopeptidase from Trichosporon cutaneum". Agric. Biol. Chem. 47: 2483–2493. 

[edit] External links

The CAS registry number for this enzyme class is 76689-19-5.

• IUBMB entry for 3.5.1.57

• KEGG entry for 3.5.1.57

• BRENDA entry for 3.5.1.57

• NiceZyme view of 3.5.1.57

• EC2PDB: PDB structures for 3.5.1.57

• PRIAM entry for 3.5.1.57

• PUMA2 entry for 3.5.1.57

• IntEnz: Integrated Enzyme entry for 3.5.1.57

• MetaCyc entry for 3.5.1.57

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050365: tryptophanamidase

• AMIGO entry for GO code 0050365: tryptophanamidase