TRPC1

Transient receptor potential cation channel, subfamily C, member 1

Identifiers

TRPC1; TRP1; HTRP-1; MGC133334; MGC133335

External IDs

Gene ontology
Molecular Function:	• ion channel activity • calcium ion binding • protein binding • store-operated calcium channel activity
Cellular Component:	• plasma membrane • integral to plasma membrane
Biological Process:	• ion transport • calcium ion transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003304 (mRNA)
NP_003295 (protein)

NM_011643 (mRNA)
NP_035773 (protein)

Location

Pubmed search

Transient receptor potential cation channel, subfamily C, member 1, also known as TRPC1, is a human gene.

[edit] See also

Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.". Pharmacol. Rev. 57 (4): 427-50. doi:10.1124/pr.57.4.6. PMID 16382100.
Rychkov G, Barritt GJ (2007). "TRPC1 Ca(2+)-permeable channels in animal cells.". Handb Exp Pharmacol (179): 23-52. doi:10.1007/978-3-540-34891-7_2. PMID 17217049.
Ambudkar IS (2007). "TRPC1: a core component of store-operated calcium channels.". Biochem. Soc. Trans. 35 (Pt 1): 96-100. doi:10.1042/BST0350096. PMID 17233611.

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v • d • e Membrane transport protein: ion channels

Ca²⁺: Calcium channel	Voltage-dependent calcium channel (L-type/Ca_vα(1.1, 1.2, 1.3, 1.4), N-type, P-type/Ca_vα(2.1), Q-type, R-type, T-type, α₂δ-subunits (1, 2), β-subunits (β1, β2, β3, β4), γ-subunits (γ1, γ2, γ3, γ4) Inositol triphosphate receptor • Ryanodine receptor • Cation channels of sperm • Two-pore channel

Na⁺: Sodium channel	Na_vα (1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.9, 7A) • Na_vβ (1, 2, 3, 4) • Epithelial sodium channel

K⁺: Potassium channel	Voltage-gated (K_vα (1.1, 1.2, 1.3, 1.4, 1.5, 2.1, 3.1, 3.4, 4.1, 4.2, 4.3, 6.1, 7.1, 7.2, 7.3, 7.4, 7.5, 9.3, 10.1, 11.1/hERG) • K_vβ (1, 2), Shaker gene, KCNE1) Calcium-activated (BK channel: α1, β1, β2, β3, β4; SK channel: SK1, SK2, SK3, SK4) Inward-rectifier K_ir (1.1, 2.1, 2.2, 2.3, 2.4, GIRK, 3.1, 3.2, 3.3, 3.4, 4.1, 4.2, 5.1, 6.1, 6.2, 7.1) Tandem pore domain K2P (1, 2, 3, 4, 6, 9, 15, 17)

Cl^-: Chloride channel	Cystic fibrosis transmembrane conductance regulator

Porin	Aquaporin (1, 2, 3, 4, 5, 7, 8, 9) • Voltage-dependent anion channel (1)

Cations: TRP	TRPA (1) • TRPC (1, 2, 3, 4, 4AP, 5, 6, 7) • TRPM (1, 2, 3, 4, 5, 6, 7, 8) • TRPML (Mucolipin-1) • TRPP (1, 2) • TRPV (1, 2, 3, 4, 5, 6)

Other/general	Voltage-gated ion channel • Ligand-gated ion channel • Cyclic nucleotide-gated ion channel (α1, α2, α3, β1, β3, H1, H2, H3, H4) • Stretch-activated ion channel