TRPA1

From Wikipedia, the free encyclopedia

Transient receptor potential cation channel, subfamily A, member 1

Identifiers

TRPA1; ANKTM1

External IDs

OMIM: 604775 MGI: 3522699 HomoloGene: 7189

Gene ontology
Molecular Function:	• ion channel activity • calcium channel activity • channel activity
Cellular Component:	• membrane fraction • integral to plasma membrane • membrane
Biological Process:	• ion transport • response to cold • response to stimulus • thermoception

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_007332 (mRNA)
NP_015628 (protein)

NM_177781 (mRNA)
NP_808449 (protein)

Location

Chr 8: 73.1 - 73.15 Mb

Chr 1: 14.86 - 14.9 Mb

Pubmed search

[1]

[2]

Transient receptor potential cation channel, subfamily A, member 1, also known as TRPA1, is a human gene.

The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control.^[1]

[edit] References

^ Entrez Gene: TRPA1 transient receptor potential cation channel, subfamily A, member 1.

[edit] Further reading

Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.". Pharmacol. Rev. 57 (4): 427-50. doi:10.1124/pr.57.4.6. PMID 16382100.
García-Añoveros J, Nagata K (2007). "TRPA1.". Handb Exp Pharmacol (179): 347-62. doi:10.1007/978-3-540-34891-7_21. PMID 17217068.