From Wikipedia, the free encyclopedia
Troponin T is a part of the troponin complex. It binds to tropomyosin, interlocking them to form a troponin-tropomyosin complex.
The tissue specific subtypes are:
- Slow skeletal troponin T1, TNNT1 (19q13.4, 191041)
- Cardiac troponin T2, TNNT2 (1q32, 191045)
- Fast skeletal troponin T3, TNNT3 (11p15.5, 600692)
Troponin T binds to tropomyosin and helps position it on actin [1]. And in a less complicated light, Troponin T modulates contraction of striated muscle [2]
[edit] References
- ^ marieb, elaine (2004)
- ^ black, joyce (2005)
[edit] External links
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Histology: muscle tissue |
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| skeletal muscle/general |
epimysium, fascicle, perimysium, endomysium, muscle fiber ( intrafusal, extrafusal), myofibril
sarcomere (a, i, and h bands; z and m lines), myofilaments (thin filament/actin, thick filament/myosin, elastic filament/titin, nebulin), tropomyosin, troponin (T, C, I)
costamere (dystrophin, α,β-dystrobrevin, syncoilin, synemin/desmuslin, dysbindin, sarcoglycan, dystroglycan, sarcospan), desmin
neuromuscular junction, motor unit, muscle spindle, excitation-contraction coupling, sliding filament mechanism
myoblast, satellite cell, sarcoplasm, sarcolemma, sarcoplasmic reticulum, T-tubule
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| cardiac muscle |
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| smooth muscle |
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Proteins of the cytoskeleton |
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| Microfilaments |
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| Intermediate filaments |
type 1 and 2 ( Cytokeratin, type I, type II) - type 3 ( Desmin, GFAP, Peripherin, Vimentin) - type 4 ( Internexin, Nestin, Neurofilament, Synemin, Syncoilin) - type 5 ( Lamin A, B)
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| Microtubules |
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| Catenins |
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| Nonhuman |
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| Other |
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