Trisomy 16

Trisomy 16 is a chromosomal abnormality in which there are three copies of chromosome 16 rather than two.^[1] It is the most common cause of miscarriage during the first trimester of pregnancy.

It is not possible for a child to be born with an extra copy of this chromosome present in all cells (called Full Trisomy 16).^[2]

It is possible to be born with the mosaic form.^[3]^[4]

[edit] External links

^ Mary Kugler, R.N. (2005-08-20). Chromosome 16 Disorders (English). About.com:Rare Diseases. About, Inc.. Retrieved on 2008-01-30.
^ Seller, MJ; Fear, C; Kumar, A; Mohammed, S (2004). "Trisomy 16 in a mid-trimester IVF foetus with multiple abnormalities". Clinical Dysmorphology 13 (3): 187–190. London: Lippincott Williams & Wilkins. ISSN 196772467. PMID 15194958. OCLC 196772467. BL Shelfmark 3286.273700.
^ Simensen, RJ; Colby, RS; Corning, KJ (2003). "A prenatal counseling conundrum: mosaic trisomy 16. A case study presenting cognitive functioning and adaptive behavior". Genetic Counselling 14 (3): 331–6. Geneva: Édition médicine et hygiène. ISSN 1015-8146. PMID 14577678. OCLC 210520912. BL Shelfmark 4111.845000.
^ Langlois, S; Yong, P J; Yong, S L; Barrett, I; Kalousek, D K; Miny, P; Exeler, R; Morris, K; Robinson, W P (2006). "Postnatal follow-up of prenatally diagnosed trisomy 16 mosaicism". Prenatal Diagnosis 26 (6): 548–558. New York: John Wiley & Sons. doi:10.1002/pd.1457. ISSN 0197-3851. PMID 16683298. OCLC 108807898. BL Shelfmark 6607.646000.

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v • d • e Pathology: chromosome abnormalities (Q90-Q99, 758)

Autosomal trisomies	Down syndrome (21), Edwards syndrome (18), Patau syndrome (13), Trisomy 9, Warkany syndrome 2 (8), Cat eye syndrome (22), Trisomy 22, Trisomy 16

Autosomal monosomies/deletions	Wolf-Hirschhorn syndrome (4), Cri du chat (5), Williams syndrome (7), Angelman syndrome/Prader-Willi syndrome (15), Miller-Dieker syndrome/Smith-Magenis syndrome (17), 22q11.2 deletion syndrome (22)

X/Y linked	Monosomy: Turner syndrome (XO) Trisomy: Triple X syndrome (XXX), Klinefelter's syndrome (XXY), XYY Other Karyotypes: XXXX, XXYY, XXXXX, XXXXY

Translocations	Philadelphia chromosome, Burkitt's lymphoma

Other	Fragile X syndrome, Gonadal dysgenesis (Mixed gonadal dysgenesis)