Trimetaphosphatase

From Wikipedia, the free encyclopedia

In enzymology, a trimetaphosphatase (EC 3.6.1.2) is an enzyme that catalyzes the chemical reaction

trimetaphosphate + H₂O triphosphate

Thus, the two substrates of this enzyme are trimetaphosphate and H₂O, whereas its product is triphosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is trimetaphosphate hydrolase. This enzyme is also called inorganic trimetaphosphatase. This enzyme participates in pyrimidine metabolism.

[edit] References

• IUBMB entry for 3.6.1.2
• BRENDA references for 3.6.1.2 (Recommended.)
• PubMed references for 3.6.1.2
• PubMed Central references for 3.6.1.2
• Google Scholar references for 3.6.1.2
• KORNBERG SR (1956). "Tripolyphosphate and trimetaphosphate in yeast extracts". J. Biol. Chem. 218: 23–31. PMID 13278311. 
• MEYERHOF O, SHATAS R, KAPLAN A (1953). "Heat of hydrolysis of trimetaphosphate". Biochim. Biophys. Acta. 12: 121–7. doi:10.1016/0006-3002(53)90130-9. PMID 13115420. 

[edit] External links

The CAS registry number for this enzyme class is 9024-84-4.

• IUBMB entry for 3.6.1.2

• KEGG entry for 3.6.1.2

• BRENDA entry for 3.6.1.2

• NiceZyme view of 3.6.1.2

• EC2PDB: PDB structures for 3.6.1.2

• PRIAM entry for 3.6.1.2

• PUMA2 entry for 3.6.1.2

• IntEnz: Integrated Enzyme entry for 3.6.1.2

• MetaCyc entry for 3.6.1.2

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050351: trimetaphosphatase

• AMIGO entry for GO code 0050351: trimetaphosphatase