Triheptanoin
From Wikipedia, the free encyclopedia
| Triheptanoin | |
|---|---|
 |
|
| IUPAC name | 1,3-Di(heptanoyloxy)propan-2-yl heptanoate |
| Identifiers | |
| CAS number | [620-67-7] |
| PubChem | |
| SMILES | CCCCCCC(=O)OCC(COC(=O)CCCCCC)OC(=O)CCCCCC |
| Properties | |
| Molecular formula | C24H44O6 |
| Molar mass | 428.60 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
|
Triheptanoin is triglyceride that is comprised of three seven-carbon fatty acids. These odd-carbon fatty acids are able to provide anaplerotic substrates for the the TCA cycle. Triheptanoin is used clinically in humans to treat inherited metabolic diseases, such as Pyruvate carboxylase deficiency. It also appears to increase the efficacy of the ketogenic diet as a treatment for epilepsy.
[edit] References
- de Almeida Rabello Oliveira M, da Rocha Ataíde T, de Oliveira SL, et al (March 2008). "Effects of short-term and long-term treatment with medium- and long-chain triglycerides ketogenic diet on cortical spreading depression in young rats". Neurosci. Lett. 434 (1): 66–70. doi:. PMID 18281154.
- Mochel F, DeLonlay P, Touati G, et al (April 2005). "Pyruvate carboxylase deficiency: clinical and biochemical response to anaplerotic diet therapy". Mol. Genet. Metab. 84 (4): 305–12. doi:. PMID 15781190.
