Trifluoroperazine

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Trifluoroperazine (TFP) is the generic name for a clinically ^[1] and experimentally ^{[2] [3] [4]} useful drug.

It has been shown to be useful in relation to schizophrenia; it works as a calmodulin inhibitor.

[edit] References

1. ^ "Marques, L O and Lima, M S and Soares, B G O" ("2004"). ""Trifluoperazine for schizophrenia"". "Cochrane Database Syst Rev": "CD003545". 
2. ^ @Article{pmid16824931, Author="Ondarza, Raul N and Iturbe, Angelica and Hernandez, Eva", Title="{In vitro antiproliferative effects of neuroleptics, antimycotics and antibiotics on the human pathogens Acanthamoeba polyphaga and Naegleria fowleri}", Journal="Arch Med Res", Year="2006", Volume="37", Number="6", Pages="723--729", Month="Aug" }
3. ^ @Article{pmid7887964, Author="Ning, Y M and Sanchez, E R", Title="{Evidence for a functional interaction between calmodulin and the glucocorticoid receptor}", Journal="Biochem Biophys Res Commun", Year="1995", Volume="208", Number="1", Pages="48--54", Month="Mar" }
4. ^ @Article{pmid7700236, Author="Bouquin, N and Tempete, M and Holland, I B and Seror, S J", Title="{Resistance to trifluoroperazine, a calmodulin inhibitor, maps to the fabD locus in Escherichia coli}", Journal="Mol Gen Genet", Year="1995", Volume="246", Number="5", Pages="628--637", Month="Mar"}