TRIT1

From Wikipedia, the free encyclopedia

TRNA isopentenyltransferase 1

Identifiers

TRIT1; FLJ20061; IPT; MGC149242; MGC149243; MOD5

External IDs

MGI: 1914216 HomoloGene: 7010

Gene ontology
Molecular Function:	• nucleotide binding • tRNA isopentenyltransferase activity • ATP binding • zinc ion binding • transferase activity • metal ion binding
Cellular Component:	• cellular_component • mitochondrion
Biological Process:	• tRNA processing

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_017646 (mRNA)
NP_060116 (protein)

NM_025873 (mRNA)
NP_080149 (protein)

Location

Chr 1: 40.08 - 40.12 Mb

Chr 4: 122.52 - 122.56 Mb

Pubmed search

[1]

[2]

TRNA isopentenyltransferase 1, also known as TRIT1, is a human gene.^[1]

[edit] References

^ Entrez Gene: TRIT1 tRNA isopentenyltransferase 1.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Golovko A, Hjälm G, Sitbon F, Nicander B (2001). "Cloning of a human tRNA isopentenyl transferase.". Gene 258 (1-2): 85-93. PMID 11111046.
Lemieux J, Lakowski B, Webb A, et al. (2002). "Regulation of physiological rates in Caenorhabditis elegans by a tRNA-modifying enzyme in the mitochondria.". Genetics 159 (1): 147-57. PMID 11560893.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Spinola M, Galvan A, Pignatiello C, et al. (2005). "Identification and functional characterization of the candidate tumor suppressor gene TRIT1 in human lung cancer.". Oncogene 24 (35): 5502-9. doi:10.1038/sj.onc.1208687. PMID 15870694.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Spinola M, Falvella FS, Galvan A, et al. (2007). "Ethnic differences in frequencies of gene polymorphisms in the MYCL1 region and modulation of lung cancer patients' survival.". Lung Cancer 55 (3): 271-7. doi:10.1016/j.lungcan.2006.10.023. PMID 17145094.