Transfusion hemosiderosis

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Transfusion hemosiderosis
Classification and external resources
ICD-9 999.8

Transfusional hemosiderosis is the accumulation of iron in the liver and/or heart but also endocrine organs, in patients who receive frequent blood transfusions (such as those with thalassemia, sickle cell disease, aplastic anemia or myelodysplastic syndrome).

Contents

[edit] Treatment

Treatment is by iron chelating agents: deferoxamine,[1] deferiprone or deferasirox. If iron overload has caused end-organ damage, this is generally irreversible and may require transplantation.

[edit] Notable patients

Ted DeVita, the "bubble boy", died of transfusional iron overload from too many blood transfusions.

[edit] See also

[edit] References

  1. ^ Cappellini MD (June 2007). "Exjade(R) (deferasirox, ICL670) in the treatment of chronic iron overload associated with blood transfusion". Ther Clin Risk Manag 3 (2): 291–9. PMID 18360637.