Transcription initiation protein SPT3 homolog

From Wikipedia, the free encyclopedia

Suppressor of Ty 3 homolog (S. cerevisiae)

Identifiers

SUPT3H; SPT3; SPT3L

External IDs

OMIM: 602947 MGI: 1923723 HomoloGene: 31184

Gene ontology
Molecular Function:	• RNA polymerase II transcription factor activity • transcription activator activity • transcription initiation factor activity
Cellular Component:	• nucleus • transcription factor complex
Biological Process:	• regulation of progression through cell cycle • transcription • transcription initiation • regulation of transcription from RNA polymerase II promoter

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_003599 (mRNA)
NP_003590 (protein)

NM_178652 (mRNA)
NP_848767 (protein)

Location

Chr 6: 44.89 - 45.45 Mb

Chr 17: 44.25 - 44.51 Mb

Pubmed search

[1]

[2]

Suppressor of Ty 3 homolog (S. cerevisiae), also known as SUPT3H, is a human gene.^[1]

[edit] References

^ Entrez Gene: SUPT3H suppressor of Ty 3 homolog (S. cerevisiae).

[edit] Further reading

Ogryzko VV, Kotani T, Zhang X, et al. (1998). "Histone-like TAFs within the PCAF histone acetylase complex.". Cell 94 (1): 35–44. PMID 9674425.
Martinez E, Kundu TK, Fu J, Roeder RG (1998). "A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID.". J. Biol. Chem. 273 (37): 23781–5. PMID 9726987.
Yu J, Madison JM, Mundlos S, et al. (1998). "Characterization of a human homologue of the Saccharomyces cerevisiae transcription factor spt3 (SUPT3H).". Genomics 53 (1): 90–6. doi:10.1006/geno.1998.5500. PMID 9787080.
Vassilev A, Yamauchi J, Kotani T, et al. (1999). "The 400 kDa subunit of the PCAF histone acetylase complex belongs to the ATM superfamily.". Mol. Cell 2 (6): 869–75. PMID 9885574.
Brand M, Yamamoto K, Staub A, Tora L (1999). "Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.". J. Biol. Chem. 274 (26): 18285–9. PMID 10373431.
Speek M (2001). "Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes.". Mol. Cell. Biol. 21 (6): 1973–85. doi:10.1128/MCB.21.6.1973-1985.2001. PMID 11238933.
Brand M, Moggs JG, Oulad-Abdelghani M, et al. (2001). "UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation.". EMBO J. 20 (12): 3187–96. doi:10.1093/emboj/20.12.3187. PMID 11406595.
Martinez E, Palhan VB, Tjernberg A, et al. (2001). "Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.". Mol. Cell. Biol. 21 (20): 6782–95. doi:10.1128/MCB.21.20.6782-6795.2001. PMID 11564863.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Cavusoglu N, Brand M, Tora L, Van Dorsselaer A (2003). "Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis.". Proteomics 3 (2): 217–23. doi:10.1002/pmic.200390030. PMID 12601814.
Liu X, Tesfai J, Evrard YA, et al. (2003). "c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation.". J. Biol. Chem. 278 (22): 20405–12. doi:10.1074/jbc.M211795200. PMID 12660246.