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| traJ 5' UTR |
 |
| Type: |
Cis-reg; |
| 2° structure: |
Predicted; ILM |
| Seed alignment: |
PubMed |
| Avg length: |
108.8 nucleotides |
| Avg identity: |
88% |
|
The traJ 5' UTR is a cis acting RNA element which is involved in regulating plasmid transfer in bacteria.
In conjugating bacteria the FinOP system regulates the transfer of F-like plasmids. The FinP gene encodes an antisense RNA product that is complementary to part of the 5' UTR of the traJ mRNA[1]. The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.
[edit] References
- ^ Arthur DC, Ghetu AF, Gubbins MJ, Edwards RA, Frost LS, Glover JN (2003). "FinO is an RNA chaperone that facilitates sense-antisense RNA interactions". EMBO J. 22 (23): 6346–55. doi:10.1093/emboj/cdg607. PMID 14633993.
[edit] External links
