TPM4

From Wikipedia, the free encyclopedia

Tropomyosin 4

Identifiers

External IDs

OMIM: 600317 MGI: 2449202 HomoloGene: 74286

Gene ontology
Molecular Function:	• actin binding • structural constituent of muscle
Cellular Component:	• cytoskeleton • muscle thin filament tropomyosin
Biological Process:	• cell motility

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003290 (mRNA)
NP_003281 (protein)

NM_001001491 (mRNA)
NP_001001491 (protein)

Location

Chr 19: 16.04 - 16.07 Mb

Chr 8: 75.06 - 75.08 Mb

Pubmed search

[1]

[2]

Tropomyosin 4, also known as TPM4, is a human gene.^[1]

[edit] References

^ Entrez Gene: TPM4 tropomyosin 4.

[edit] Further reading

Rasmussen HH, van Damme J, Puype M, et al. (1993). "Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.". Electrophoresis 13 (12): 960-9. PMID 1286667.
MacLeod AR, Talbot K, Smillie LB, Houlker C (1987). "Characterization of a cDNA defining a gene family encoding TM30p1, a human fibroblast tropomyosin.". J. Mol. Biol. 194 (1): 1-10. PMID 3612796.
MacLeod AR, Houlker C, Reinach FC, et al. (1986). "A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism.". Proc. Natl. Acad. Sci. U.S.A. 82 (23): 7835-9. PMID 3865200.
Wilton SD, Lim L, Dorosz SD, et al. (1996). "Assignment of the human alpha-tropomyosin gene TPM4 to band 19p13.1 by fluorescence in situ hybridization.". Cytogenet. Cell Genet. 72 (4): 294-6. PMID 8641132.
Lawrence B, Perez-Atayde A, Hibbard MK, et al. (2000). "TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors.". Am. J. Pathol. 157 (2): 377-84. PMID 10934142.
Meech SJ, McGavran L, Odom LF, et al. (2001). "Unusual childhood extramedullary hematologic malignancy with natural killer cell properties that contains tropomyosin 4--anaplastic lymphoma kinase gene fusion.". Blood 98 (4): 1209-16. PMID 11493472.
Yi J, Kloeker S, Jensen CC, et al. (2002). "Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers.". J. Biol. Chem. 277 (11): 9580-9. doi:10.1074/jbc.M106922200. PMID 11782456.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.". Nat. Biotechnol. 21 (5): 566-9. doi:10.1038/nbt810. PMID 12665801.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Lin KT, Lu RM, Tarn WY (2004). "The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo.". Mol. Cell. Biol. 24 (20): 9176-85. doi:10.1128/MCB.24.20.9176-9185.2004. PMID 15456888.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Bruneel A, Labas V, Mailloux A, et al. (2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis.". Proteomics 5 (15): 3876-84. doi:10.1002/pmic.200401239. PMID 16130169.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.