TP73L

From Wikipedia, the free encyclopedia


Tumor protein p73-like
PDB rendering based on 1rg6.
Available structures: 1rg6
Identifiers
Symbol(s) TP73L; p63; B(p51A); B(p51B); EEC3; KET; LMS; OFC8; RHS; SHFM4; TP63; p51; p73H; p73L
External IDs OMIM: 603273 MGI1330810 HomoloGene31189
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 8626 22061
Ensembl ENSG00000073282 ENSMUSG00000022510
Uniprot Q9H3D4 O88898
Refseq NM_003722 (mRNA)
NP_003713 (protein)
NM_011641 (mRNA)
NP_035771 (protein)
Location Chr 3: 190.83 - 191.1 Mb Chr 16: 25.6 - 25.81 Mb
Pubmed search [1] [2]

Tumor protein p73-like, also known as TP73L, is a human gene. It is associated with ectrodactyly-ectodermal dysplasia-cleft syndrome and Hay-Wells syndrome.


[edit] Further reading

  • Little NA, Jochemsen AG (2002). "p63.". Int. J. Biochem. Cell Biol. 34 (1): 6–9. PMID 11733180. 
  • van Bokhoven H, McKeon F (2002). "Mutations in the p53 homolog p63: allele-specific developmental syndromes in humans.". Trends in molecular medicine 8 (3): 133–9. PMID 11879774. 
  • van Bokhoven H, Brunner HG (2002). "Splitting p63.". Am. J. Hum. Genet. 71 (1): 1–13. PMID 12037717. 
  • Brunner HG, Hamel BC, Bokhoven Hv H (2003). "P63 gene mutations and human developmental syndromes.". Am. J. Med. Genet. 112 (3): 284–90. doi:10.1002/ajmg.10778. PMID 12357472. 
  • Jacobs WB, Walsh GS, Miller FD (2005). "Neuronal survival and p73/p63/p53: a family affair.". The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 10 (5): 443–55. doi:10.1177/1073858404263456. PMID 15359011. 
  • Zusman I (2005). "The soluble p51 protein in cancer diagnosis, prevention and therapy.". In Vivo 19 (3): 591–8. PMID 15875781. 
  • Morasso MI, Radoja N (2005). "Dlx genes, p63, and ectodermal dysplasias.". Birth Defects Res. C Embryo Today 75 (3): 163–71. doi:10.1002/bdrc.20047. PMID 16187309. 
  • Barbieri CE, Pietenpol JA (2006). "p63 and epithelial biology.". Exp. Cell Res. 312 (6): 695–706. doi:10.1016/j.yexcr.2005.11.028. PMID 16406339. 


[edit] External links