Tombusvirus 3' UTR region IV
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Tombusvirus 3' UTR is an important cis-regulatory region of the Tombus virus genome[1].
Tomato bushy stunt virus is the prototype member of the Tombusviridae family. The genome of this virus is positive sense single stranded RNA. Replication occurs via a negative strand RNA intermediate. In addition to viral proteins p33 and the RNA-dependent RNA polymerase p92, and unknown host factors, conserved and structural regions within the 3'untranslated region (3'UTR) are important for regulating genome replication. This 3' structural element contains a pseudoknot [2].
[edit] References
- ^ Fabian MR, Na H, Ray D, White KA (2003). "3'-Terminal RNA secondary structures are important for accumulation of tomato bushy stunt virus DI RNAs". Virology 313 (2): 567–80. PMID 12954222.
- ^ <ref>{{cite journal | author = Pogany J, Fabian MR, White KA, Nagy PD | title = A replication silencer element in a plus-strand RNA virus | journal = EMBO J. | volume = 22 | issue = 20 | pages = 5602–11 | year = 2003 | pmid = 14532132 | doi = 10.1093/emboj/cdg523}}</li></ol></ref>