Tombus virus defective interfering (DI) RNA region 3

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Tombus virus defective interfering (DI) RNA region 3
Template:Abbreviation
Type: Cis-reg;
2° structure: Published; PubMed
Seed alignment: PubMed
Avg length: 69.6 nucleotides
Avg identity: 79%

Tombus virus defective interfering (DI) RNA region 3 is an important cis-regulatory region identified in the 3'UTR of Tombus virus defective interfering (DI) particles (DI)[1].

Defective interfering RNAs are small sub-viral replicons which are non-coding deletion mutants of the virus that maintain cis-acting RNA elements necessary for replication of the host virus [1]. This conserved region of the 3'UTR has been found to enhance DI RNA accumulation by approximately 10-fold as well as mediating viral replication[1].

[edit] References

  1. ^ a b c Ray D, White KA (2003). "An internally located RNA hairpin enhances replication of Tomato bushy stunt virus RNAs". J. Virol. 77 (1): 245–57. PMID 12477830. 

[edit] External links