TOMM40

From Wikipedia, the free encyclopedia

Translocase of outer mitochondrial membrane 40 homolog (yeast)

Identifiers

TOMM40; C19orf1; D19S1177E; PER-EC1; PEREC1; TOM40

External IDs

OMIM: 608061 MGI: 1858259 HomoloGene: 39966

Gene ontology
Molecular Function:	• molecular_function • voltage-gated ion-selective channel activity
Cellular Component:	• mitochondrion • mitochondrial outer membrane • membrane • integral to membrane • outer membrane
Biological Process:	• protein targeting to mitochondrion • anion transport • protein transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_006114 (mRNA)
NP_006105 (protein)

NM_016871 (mRNA)
NP_058567 (protein)

Location

Chr 19: 50.09 - 50.1 Mb

n/a

Pubmed search

[1]

[2]

Translocase of outer mitochondrial membrane 40 homolog (yeast), also known as TOMM40, is a human gene.^[1]

[edit] References

^ Entrez Gene: TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast).

[edit] Further reading

Walker LC, Waddell N, Ten Haaf A, et al.. "Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers.". doi:10.1007/s10549-007-9848-5. PMID 18095154.
Szafranski K, Schindler S, Taudien S, et al. (2008). "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.". Genome Biol. 8 (8): R154. doi:10.1186/gb-2007-8-8-r154. PMID 17672918.
Borowsky ME, Das B, Axiotis CA, et al. (2006). "Haymaker gene expression in malignant and normal gynecologic tissues.". J. Histochem. Cytochem. 54 (7): 753–61. doi:10.1369/jhc.5A6765.2006. PMID 16495475.
Humphries AD, Streimann IC, Stojanovski D, et al. (2005). "Dissection of the mitochondrial import and assembly pathway for human Tom40.". J. Biol. Chem. 280 (12): 11535–43. doi:10.1074/jbc.M413816200. PMID 15644312.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Johnston AJ, Hoogenraad J, Dougan DA, et al. (2003). "Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane.". J. Biol. Chem. 277 (44): 42197–204. doi:10.1074/jbc.M205613200. PMID 12198123.
Das B, Tao SZ, Mushnitsky R, Norin AJ (2002). "Genetic identity and differential expression of p38.5 (Haymaker) in human malignant and nonmalignant cells.". Int. J. Cancer 94 (6): 800–6. PMID 11745481.
Suzuki H, Okazawa Y, Komiya T, et al. (2001). "Characterization of rat TOM40, a central component of the preprotein translocase of the mitochondrial outer membrane.". J. Biol. Chem. 275 (48): 37930–6. doi:10.1074/jbc.M006558200. PMID 10980201.
Freitas EM, Zhang WJ, Lalonde JP, et al. (1999). "Sequencing of 42kb of the APO E-C2 gene cluster reveals a new gene: PEREC1.". DNA Seq. 9 (2): 89–100. PMID 10520737.