Tolfenamic acid
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Tolfenamic acid
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Systematic (IUPAC) name | |
2-[(3-chloro-2-methylphenyl)amino]benzoic acid)."[1] | |
Identifiers | |
CAS number | |
ATC code | ? |
PubChem | |
Chemical data | |
Formula | C14H12ClNO2 |
Mol. mass | 261.707 |
Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
? |
Legal status | |
Routes | oral |
Tolfenamic acid (TA) is one of the class of non steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.
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[edit] Other possible uses
- A study concludes, "TA was found significantly better than placebo in the subjective evaluation of drug efficacy (p<0.001) and in reducing the reported hangover symptoms in general (p < 0.01). In the TA group, significantly lower symptom scores were obtained for headache (p<0.01), and for nausea, vomiting, irritation, tremor, thirst and dryness of mouth (all p < 0.05)."[2]
[edit] Commercial names
Commercial names for tolfenamic acid include:
[edit] External links
[edit] References
- ^ Kim Vilbour Andersen, Sine Larsen, Børge Alhede, Niels Gelting and Ole Buchardt Characterization of two polymorphic forms of tolfenamic acid, N-(2-methyl-3-chlorophenyl)anthranilic acid: their crystal structures and relative stabilities J. Chem. Soc., Perkin Trans. 2, 1989, 1443 - 1447, DOI:10.1039/P29890001443
- ^ S. Kaivola1, J. Parantainen, T. Österman and H. Timonen Hangover headache and prostaglandins: Prophylactic treatment with tolfenamic acid Cephalalgia Volume 3 Page 31 - March 1983 doi:10.1046/j.1468-2982.1983.0301031.x
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