User:TimVickers

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My kitten Loki is wonderful.
My kitten Loki is wonderful.

Hi, I'm Tim Vickers, glad to be here.

I am a biochemist with interests in tropical diseases and enzymology. I did my PhD in biochemistry at Dundee University in Scotland under the supervision of Alan Fairlamb and am now working in America.

If anybody has any questions about these topics I would be delighted to try to help. I am usually glad to answer questions and research stuff for articles, after all, favours owed are valuable things.

At the moment I'm the director of Molecular and Cellular Biology wikiproject and working on bringing as many basic molecular biology, biochemistry and infectious disease articles up to FA level as I can. Even with the help of all the expert editors in the project, this is going to be a very long process, but generations of students will bless our efforts as they plagiarise our text!

The MCB project is a group of editors interested in improving the quality of Wikipedia articles on molecular life sciences. Since these pages are usually the top Google hit on any biochemical subject you care to mention, this is more important from an academic viewpoint than you might think. Anybody interested in helping out can sign up on the project page. You will be most welcome.

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This user is a member of the Molecular & Cellular Biology WikiProject

Wyllie S, Vickers TJ, Fairlamb AH. Roles of trypanothione S-transferase and tryparedoxin peroxidase in resistance to antimonials Antimicrob Agents Chemother. 2008 Feb 4 (Epub ahead of print)

Scott DA, Hickerson SM, Vickers TJ, Beverley SM. The role of the mitochondrial glycine cleavage complex in the metabolism and virulence of the protozoan parasite Leishmania major. J Biol Chem. 2008 Jan 4;283(1):155-65.

Vickers TJ, Orsomando G, de la Garza RD, Scott DA, Kang SO, Hanson AD, Beverley SM. Biochemical and genetic analysis of methylenetetrahydrofolate reductase in leishmania metabolism and virulence. J Biol Chem. 2006 Dec 15;281(50):38150-8.

Greig N, Wyllie S, Vickers TJ, Fairlamb AH. Trypanothione-dependent glyoxalase I in Trypanosoma cruzi. Biochem J. 2006 Dec 1;400(2):217-23.

Ariza A, Vickers TJ, Greig N, Armour KA, Dixon MJ, Eggleston IM, Fairlamb AH, Bond CS. Specificity of the trypanothione-dependent Leishmania major glyoxalase I: structure and biochemical comparison with the human enzyme. Mol Microbiol. 2006 Feb;59(4):1239-48.

Vickers TJ, Greig N, Fairlamb AH. A trypanothione-dependent glyoxalase I with a prokaryotic ancestry in Leishmania major. Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13186-91.

Vickers TJ, Wyllie S, Fairlamb AH. Leishmania major elongation factor 1B complex has trypanothione S-transferase and peroxidase activity. J Biol Chem. 2004 Nov 19;279(47):49003-9.

Saravanamuthu A, Vickers TJ, Bond CS, Peterson MR, Hunter WN, Fairlamb AH. Two interacting binding sites for quinacrine derivatives in the active site of trypanothione reductase: a template for drug design. J Biol Chem. 2004 Jul 9;279(28):29493-500.

Vickers TJ, Fairlamb AH. Trypanothione S-transferase activity in a trypanosomatid ribosomal elongation factor 1B. J Biol Chem. 2004 Jun 25;279(26):27246-56.

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