TIMM23

From Wikipedia, the free encyclopedia

Translocase of inner mitochondrial membrane 23 homolog (yeast)

Identifiers

TIMM23; MGC22767; PRO1197; TIM23; TIMM23B

External IDs

OMIM: 605034 MGI: 1858317 HomoloGene: 9651

Gene ontology
Molecular Function:	• protein binding • protein transmembrane transporter activity
Cellular Component:	• mitochondrion • mitochondrial inner membrane presequence translocase complex • mitochondrial intermembrane space • integral to plasma membrane • membrane • outer membrane
Biological Process:	• protein targeting to mitochondrion • intracellular protein transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

XM_001133798 (mRNA)
XP_001133798 (protein)

NM_016897 (mRNA)
NP_058593 (protein)

Location

Chr 10: 51.26 - 51.29 Mb

n/a

Pubmed search

[1]

[2]

Translocase of inner mitochondrial membrane 23 homolog (yeast), also known as TIMM23, is a human gene.^[1]

[edit] References

^ Entrez Gene: TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast).

[edit] Further reading

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Guo Y, Cheong N, Zhang Z, et al. (2004). "Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death.". J. Biol. Chem. 279 (23): 24813–25. doi:10.1074/jbc.M402049200. PMID 15044455.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Yamamoto H, Esaki M, Kanamori T, et al. (2002). "Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes.". Cell 111 (4): 519–28. PMID 12437925.
Moro F, Sirrenberg C, Schneider HC, et al. (1999). "The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix.". EMBO J. 18 (13): 3667–75. doi:10.1093/emboj/18.13.3667. PMID 10393182.
Bauer MF, Gempel K, Reichert AS, et al. (1999). "Genetic and structural characterization of the human mitochondrial inner membrane translocase.". J. Mol. Biol. 289 (1): 69–82. doi:10.1006/jmbi.1999.2751. PMID 10339406.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.