TIMM22

From Wikipedia, the free encyclopedia

Translocase of inner mitochondrial membrane 22 homolog (yeast)

Identifiers

TIMM22; TEX4; TIM22

External IDs

OMIM: 607251 MGI: 1929742 HomoloGene: 32173

Gene ontology
Molecular Function:	• protein binding • protein transporter activity
Cellular Component:	• mitochondrion • mitochondrial inner membrane • membrane • integral to membrane
Biological Process:	• protein targeting • protein transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_013337 (mRNA)
NP_037469 (protein)

NM_019818 (mRNA)
NP_062792 (protein)

Location

Chr 17: 0.85 - 0.85 Mb

Chr 11: 76.22 - 76.23 Mb

Pubmed search

[1]

[2]

Translocase of inner mitochondrial membrane 22 homolog (yeast), also known as TIMM22, is a human gene.^[1]

[edit] References

^ Entrez Gene: TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast).

[edit] Further reading

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Mühlenbein N, Hofmann S, Rothbauer U, Bauer MF (2004). "Organization and function of the small Tim complexes acting along the import pathway of metabolite carriers into mammalian mitochondria.". J. Biol. Chem. 279 (14): 13540–6. doi:10.1074/jbc.M312485200. PMID 14726512.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Kovermann P, Truscott KN, Guiard B, et al. (2002). "Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel.". Mol. Cell 9 (2): 363–73. PMID 11864609.
Bauer MF, Rothbauer U, Mühlenbein N, et al. (2000). "The mitochondrial TIM22 preprotein translocase is highly conserved throughout the eukaryotic kingdom.". FEBS Lett. 464 (1-2): 41–7. PMID 10611480.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.