Image:Thymidylate synthase 1HVY.png

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Description

Ribbon diagram of human thymidylate synthase in complex with deoxyuridine monophosphate (orange) and the enzyme inhibitor raltitrexed (lime green).
Created using Accelrys DS Visualizer Pro 1.6 and the GIMP.

Legend

██ A unit

██ B unit

██ Deoxyuridine monophosphate (dUMP)

██ Raltitrexed
Source

From PDB entry 1HVY. More information:

  • Phan J, Koli S, Minor W, Dunlap RB, Berger SH, Lebioda L (2001). "Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug". Biochemistry 40 (7): 1897–902. PMID 11329255.
Date

August 28, 2007
Author

Fvasconcellos 17:46, 28 August 2007 (UTC)
Permission
(Reusing this image)
Public domain I, the copyright holder of this work, hereby release it into the public domain. This applies worldwide.

In case this is not legally possible:
I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law.

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File history

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Date/TimeDimensionsUserComment
current17:46, 28 August 20071,000×770 (407 KB)Fvasconcellos ({{Information |Description=Ribbon diagram of human {{w|thymidylate synthase}} in complex with {{w|deoxyuridine monophosphate}} (orange) and the {{w|enzyme inhibitor}} {{w|raltitrexed}} (lime green).<br>Created using [http://www.accelrys.com/products/downl)
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