User talk:Thshaffer

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[edit] Welcome!

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[edit] Liquid ventilation

I've fixed up the references you added: please see how it was done. I disagree with you that some aspects of total liquid ventilation are easier than gas: it most definitely IS harder to oxygenate and scrub fluorocarbon than it is to simply blend ingoing oxygen, and remove CO2 by simple ventilation and exhaust to the air (whereas liquid must be recycled as in a rebreather or anesthesia circuit). However, you may be right that control of volumes is inherently easier than with a gas. Could you explain why? SBHarris 21:57, 28 January 2008 (UTC)

Thanks for the help with the references. Regarding TLV, for infants, we have gone back to the concept of ventilating with pre-oxygenated, warmed PFC which has plenty of oxygen(one-way system) and no carbon dioxide(Lancet, 1989). To ventilate infants, it takes less than a liter of pre-oxygenated PFC to effectively recruit alveoli and stabilize the infant's under-inflated lungs during a transient period of TLV. After returning to gas ventilation (some would call this PLV), our PFC sensors in the expired gas line indicate the amount of PFC which is required to maintain an effective PFC volume in the lung. In the intensive care setting, determination of effective lung volume (FRC) is one of the most difficult variables to assess, but not for PFC in the lung.

Also using TLV circuits for larger patients, using microprocessor controlled ventilators, we can carefully control tidal volume and FRC during each phase of ventilation as described in the Heckman et al. article. As compared to our early ventilators, we no longer use patient weight as a measure of PFC in the lungs, we have the membrane and PFC loss technology greatly improved. There is a significant amount of technology and TLV results published (PubMed), but it is difficult to get all of this information across at once.--Thshaffer (talk) 00:15, 29 January 2008 (UTC)

I'm going to copy this discussion over to the liquid ventilation TALK page and continue it there. SBHarris 02:10, 29 January 2008 (UTC)