Talk:Thrombocytopenia

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1 Reaction
2 Genetic Causes
3 Immunotherepy
4 Synchronize with Heparin-induced thrombocytopenia and thrombosis (HITT)

[edit] Reaction

I reacted to an anticoagulation medicine in the hospital (Reopro)and wound up having thrombocytopenia and having to have 4 bags of platelets. What a scary disease, I had purple bruises from my head to my toes. -- Williamb (talk • contribs • logs) 04:59, 30 June 2004 (UTC)

Although rare, it is possible to get thrombocytopenia from malaria as well. Enlarged spleen is the key identifier of this. (Along with all of the normal bruising, etc.) I had this, and it dropped my platelet count below 1,000. (Normal ranges are from about 120,000 to 400,000) I thought I might add this as it is not on the causes list. 212.143.118.240 (talk • contribs • logs) 06:46, 21 June 2006 (UTC)

[edit] Genetic Causes

As a layperson without any medical background, I'm hesitant to edit an article like this, but should it also mention genetic causes of Thrombocytopenia? (e.g. TAR syndrome which both my brothers-in-law have) dramatic 07:46, 25 September 2006 (UTC)

Dramatic, you have an excellent point, and this seems to have been overlooked.--Dr.michael.benjamin 04:03, 15 February 2007 (UTC)

Amgen has filed for the approval of Romiplostim with the FDA. Romiplostim, a thrombopoiesis stimulating Fc fusion protein (peptibody), potentially represents a new approach to treating ITP by working to increase platelet production and sustain platelet levels for as long as needed. Romiplostim works similarly to thrombopoietin (TPO), a natural protein in the body. It contains an active peptide component that stimulates the TPO receptor, which is necessary for growth and maturation of the bone marrow cells that produce platelets and therefore, plays an important role in increasing platelet production. —Preceding unsigned comment added by 198.176.189.201 (talk) 16:13, 26 October 2007 (UTC)

[edit] Immunotherepy

While technically not a drug, Interleukin-2 therapy is known to induce thrombocytopenia in some patients through platelet destruction by the immune system. The effect increases over increasing cycles. This may be too specialized for inclusion. —Preceding unsigned comment added by Miglewis (talk • contribs) 15:06, 9 May 2008 (UTC)