Thiouracil

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Thiouracil
IUPAC name 2-thioxo-1H-pyrimidin-4-one
Identifiers
CAS number [141-90-2]
PubChem 1269845
MeSH Thiouracil
SMILES C1=CNC(=S)NC1=O
Properties
Molecular formula C4H4N2OS
Molar mass 128.153
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Thiouracil refers both to a specific molecule consisting of a sulfated uracil, and a family of molecules based upon that structure. The substance is a historically relevant antithyroid preparation; Astwood E.B. used it in 1943 as therapy of the Graves' disease for the first time. [1]


[edit] Reference

  1. ^ Gerabek W.: Enzyklopädie Medizingeschichte, S 152, 2005
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