Thiosulfate-dithiol sulfurtransferase

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In enzymology, a thiosulfate-dithiol sulfurtransferase (EC 2.8.1.5) is an enzyme that catalyzes the chemical reaction

thiosulfate + dithioerythritol sulfite + 4,5-cis-dihydroxy-1,2-dithiacyclohexane (i.e. oxidized dithioerythritol) + sulfide

Thus, the two substrates of this enzyme are thiosulfate and dithioerythritol, whereas its 3 products are sulfite, 4,5-cis-dihydroxy-1,2-dithiacyclohexane, and sulfide.

This enzyme belongs to the family of transferases, specifically the sulfurtransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is thiosulfate:dithioerythritol sulfurtransferase. Other names in common use include thiosulfate reductase, and TSR. This enzyme participates in sulfur metabolism.

[edit] References

• IUBMB entry for 2.8.1.5
• BRENDA references for 2.8.1.5 (Recommended.)
• PubMed references for 2.8.1.5
• PubMed Central references for 2.8.1.5
• Google Scholar references for 2.8.1.5
• Schmidt A, Erdle I and Gamon B (1984). "Isolation and characterization of thiosulfate reductases from the green alga Chlorella fusca". Planta 162: 243–249. 

[edit] External links

The CAS registry number for this enzyme class is 9059-49-8.

• IUBMB entry for 2.8.1.5

• KEGG entry for 2.8.1.5

• BRENDA entry for 2.8.1.5

• NiceZyme view of 2.8.1.5

• EC2PDB: PDB structures for 2.8.1.5

• PRIAM entry for 2.8.1.5

• PUMA2 entry for 2.8.1.5

• IntEnz: Integrated Enzyme entry for 2.8.1.5

• MetaCyc entry for 2.8.1.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047362: thiosulfate-dithiol sulfurtransferase

• AMIGO entry for GO code 0047362: thiosulfate-dithiol sulfurtransferase