Theodor Boveri
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Theodor Heinrich Boveri (October 12, 1862–October 15, 1915) was a German biologist whose work with sea urchins showed that it was necessary to have all chromosomes present in order for proper embryonic development to take place. This discovery was an important part of the Boveri-Sutton chromosome theory. His other significant discovery was the centrosome (1888), which he described as the especial organ of cell division. Boveri also had discovered a phenomenon of chromatin diminution in early embryonic development of nematode Parascaris.
He also reasoned that a cancerous tumor begins with a single cell in which the make up of its chromosomes becomes scrambled, causing the cells to divide uncontrollably.
It was only much later in the twentieth century that leading researchers came to believe that Boveri may have been correct.
[edit] References
- Baltzer, Fritz (1967), Theodor Boveri: The Life of a Great Biologist 1862-1915, <http://www.devbio.com/article.php?ch=7&id=75>. Retrieved on 22 July 2007. Extract published in Gilbert, SF (2006), DevBio: a companion to Developmental Biology, 8th ed., Sinauer Associates
- Boveri, Theodor (2008), “Concerning The Origin of Malignant Tumours”, Journal of Cell Science 121 (Supplement 1): 1-84, <http://jcs.biologists.org/cgi/content/full/121/Supplement_1/1>
- Maderspacher, Florian (2008), “Theodor Boveri and the natural experiment”, Current Biology 18: R279-R286, <http://dx.doi.org/10.1016/j.cub.2008.02.061>
[edit] Further reading
- Jane, Oppenheimer (1970-80). "Boveri, Theodor". Dictionary of Scientific Biography 2. New York: Charles Scribner's Sons. 361-365. ISBN 0684101149.
[edit] External links
- Wolbert, Peter, Theodor Boveri (1862-1915), Biocenter of the University of Wuerzburg, <http://www.biozentrum2.uni-wuerzburg.de/en/more_infos/theodor_boveri_1862-1915/>. Retrieved on 22 July 2007
- Fritz Baltzer. (1967). excerpt from Theodor Boveri: The life of a great biologist, 1862-1915. University of California Press, Berkeley; pp. 85-97.