THAP7

From Wikipedia, the free encyclopedia

THAP domain containing 7

Identifiers

THAP7; MGC10963

External IDs

OMIM: 609518 MGI: 1916259 HomoloGene: 12293

Gene ontology
Molecular Function:	• DNA binding • zinc ion binding • metal ion binding
Cellular Component:	• chromosome
Biological Process:	• transcription • regulation of transcription, DNA-dependent

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001008695 (mRNA)
NP_001008695 (protein)

NM_026909 (mRNA)
NP_081185 (protein)

Location

Chr 22: 19.68 - 19.69 Mb

Chr 16: 17.44 - 17.44 Mb

Pubmed search

[1]

[2]

THAP domain containing 7, also known as THAP7, is a human gene.^[1]

[edit] References

^ Entrez Gene: THAP7 THAP domain containing 7.

[edit] Further reading

Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer.". Mamm. Genome 16 (12): 942-54. doi:10.1007/s00335-005-0075-2. PMID 16341674.
Macfarlan T, Parker JB, Nagata K, Chakravarti D (2006). "Thanatos-associated protein 7 associates with template activating factor-Ibeta and inhibits histone acetylation to repress transcription.". Mol. Endocrinol. 20 (2): 335-47. doi:10.1210/me.2005-0248. PMID 16195249.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Macfarlan T, Kutney S, Altman B, et al. (2005). "Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor.". J. Biol. Chem. 280 (8): 7346-58. doi:10.1074/jbc.M411675200. PMID 15561719.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome.". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.
Roussigne M, Kossida S, Lavigne AC, et al. (2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase.". Trends Biochem. Sci. 28 (2): 66-9. PMID 12575992.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.