TFEC

From Wikipedia, the free encyclopedia

Transcription factor EC

Identifiers

TFEC; TCFEC; TFECL

External IDs

OMIM: 604732 MGI: 1333760 HomoloGene: 32148

Gene ontology
Molecular Function:	• transcription factor activity • transcription coactivator activity • transcription corepressor activity • transcription regulator activity
Cellular Component:	• nucleus
Biological Process:	• regulation of transcription

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001018058 (mRNA)
NP_001018068 (protein)

NM_031198 (mRNA)
NP_112475 (protein)

Location

Chr 7: 115.36 - 115.46 Mb

Chr 6: 16.78 - 16.85 Mb

Pubmed search

[1]

[2]

Transcription factor EC, also known as TFEC, is a human gene.^[1]

[edit] References

^ Entrez Gene: TFEC transcription factor EC.

[edit] Further reading

Zhao GQ, Zhao Q, Zhou X, et al. (1993). "TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation.". Mol. Cell. Biol. 13 (8): 4505–12. PMID 8336698.
Yasumoto K, Shibahara S (1997). "Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator.". Biochim. Biophys. Acta 1353 (1): 23–31. PMID 9256061.
Steingrímsson E, Tessarollo L, Reid SW, et al. (1999). "The bHLH-Zip transcription factor Tfeb is essential for placental vascularization.". Development 125 (23): 4607–16. PMID 9806910.
Chung MC, Kim HK, Kawamoto S (2001). "TFEC can function as a transcriptional activator of the nonmuscle myosin II heavy chain-A gene in transfected cells.". Biochemistry 40 (30): 8887–97. PMID 11467950.
Mansky KC, Sulzbacher S, Purdom G, et al. (2002). "The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate the tartrate-resistant acid phosphatase promoter.". J. Leukoc. Biol. 71 (2): 304–10. PMID 11818452.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.