Talk:Tegaserod
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Just caught the end of the new Zelnorm ad. It looks like it's approved for men now. Can anyone confirm that? --Spikey 04:05, Jun 7, 2005 (UTC)
I guess so, since I got perscribted it today, and I'm a man. Maximumlobster 23:00, 20 December 2005 (UTC)m
[edit] Wrong Molecule
The molecule in this Wikipedia article does not appear to be the same as the molecule in the PI (Zelnorm PI).
Actually, unless I'm missing something big here, most of the chemical information appears to be wrong. Also from the PI:
"Zelnorm® (tegaserod maleate) tablets contain tegaserod as the hydrogen maleate salt. As the maleate salt, tegaserod is chemically designated as 3-(5-methoxy-1H-indol-3-ylmethylene)-N- pentylcarbazimidamide hydrogen maleate. Its empirical formula is C16H23N5O•C4H4O4. The molecular weight is 417.47..." --216.139.146.106 20:51, 9 August 2006 (UTC)
- I modeled the molecule using the SMILES provided on the tegaserod PubChem entry. As for the rest of the information provided in the infobox, such as empirical formula and molecular weight, it refers to the active moiety only ("tegaserod" itself), not to the salt (maleate) form of tegaserod, as is standard on most drug pages. I do not feel it is necessary, but I will be happy to add information for both if you feel it is relevant (you could also do it yourself, of course). Fvasconcellos 21:40, 9 August 2006 (UTC)
[edit] Changes March 30, 2007
I made two small changes that I felt I should doc on the tp. First, I changed The FDA discovered... to The FDA alleges... because apparently there is some discord between the FDA and Novartis on these symptoms. Secondly, I changed the reference for Novartis' assertion to a PDF press release because chances are that homepage will change and no longer be a press release on the front page. That's all // 3R1C 23:30, 30 March 2007 (UTC)
- Good idea. I thought of using the press release directly, and chose not to... bad choice apparently :) Fvasconcellos 00:03, 31 March 2007 (UTC)
