TEGT

From Wikipedia, the free encyclopedia


Testis enhanced gene transcript (BAX inhibitor 1)
Identifiers
Symbol(s) TEGT; BI-1; TMBIM6
External IDs OMIM: 600748 MGI99682 HomoloGene2419
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 7009 110213
Ensembl ENSG00000139644 ENSMUSG00000023010
Uniprot P55061 Q4KKX5
Refseq NM_003217 (mRNA)
NP_003208 (protein)
NM_026669 (mRNA)
NP_080945 (protein)
Location Chr 12: 48.42 - 48.44 Mb Chr 15: 99.23 - 99.24 Mb
Pubmed search [1] [2]

Testis enhanced gene transcript (BAX inhibitor 1), also known as TEGT, is a human gene.[1]


[edit] References

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Walter L, Marynen P, Szpirer J, et al. (1996). "Identification of a novel conserved human gene, TEGT.". Genomics 28 (2): 301–4. doi:10.1006/geno.1995.1145. PMID 8530040. 
  • Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags.". Genome Res. 6 (9): 807–28. PMID 8889549. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Xu Q, Reed JC (1998). "Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast.". Mol. Cell 1 (3): 337–46. PMID 9660918. 
  • Cowling RT, Birnboim HC (1999). "Preliminary characterization of the protein encoded by human testis-enhanced gene transcript (TEGT).". Mol. Membr. Biol. 15 (4): 177–87. PMID 10087504. 
  • Jean JC, Oakes SM, Joyce-Brady M (1999). "The Bax inhibitor-1 gene is differentially regulated in adult testis and developing lung by two alternative TATA-less promoters.". Genomics 57 (2): 201–8. doi:10.1006/geno.1999.5761. PMID 10198159. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Grzmil M, Thelen P, Hemmerlein B, et al. (2003). "Bax inhibitor-1 is overexpressed in prostate cancer and its specific down-regulation by RNA interference leads to cell death in human prostate carcinoma cells.". Am. J. Pathol. 163 (2): 543–52. PMID 12875974. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560. 
  • Tanaka R, Ishiyama T, Uchihara T, et al. (2006). "Expression of the Bax inhibitor-1 gene in pulmonary adenocarcinoma.". Cancer 106 (3): 648–53. doi:10.1002/cncr.21639. PMID 16353209. 
  • Lee GH, Kim HK, Chae SW, et al. (2007). "Bax inhibitor-1 regulates endoplasmic reticulum stress-associated reactive oxygen species and heme oxygenase-1 expression.". J. Biol. Chem. 282 (30): 21618–28. doi:10.1074/jbc.M700053200. PMID 17526500.