TCEAL4

From Wikipedia, the free encyclopedia


Transcription elongation factor A (SII)-like 4
Identifiers
Symbol(s) TCEAL4; DKFZp686M0279; FLJ21174; NPD017
External IDs HomoloGene88900
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 79921 n/a
Ensembl ENSG00000133142 n/a
Uniprot Q96EI5 n/a
Refseq NM_001006935 (mRNA)
NP_001006936 (protein)
n/a (mRNA)
n/a (protein)
Location Chr X: 102.72 - 102.73 Mb n/a
Pubmed search [1] n/a

Transcription elongation factor A (SII)-like 4, also known as TCEAL4, is a human gene.[1]

This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. Multiple family members are located on the X chromosome. Alternative splicing occurs for this gene; however, the full-length nature of all transcript variants has not yet been described.[1]

[edit] References

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Pillutla RC, Shimamoto A, Furuichi Y, Shatkin AJ (1999). "Genomic structure and chromosomal localization of TCEAL1, a human gene encoding the nuclear phosphoprotein p21/SIIR.". Genomics 56 (2): 217–20. doi:10.1006/geno.1998.5705. PMID 10051408. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Lu XW, Yin JY, Cui LX (2004). "[Cloning of human B lymphocyte activation-related novel gene]". Zhongguo Yi Xue Ke Xue Yuan Xue Bao 23 (1): 27–31. PMID 12905813. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325–37. doi:10.1038/nature03440. PMID 15772651. 
  • Akaishi J, Onda M, Okamoto J, et al. (2006). "Down-regulation of transcription elogation factor A (SII) like 4 (TCEAL4) in anaplastic thyroid cancer.". BMC Cancer 6: 260. doi:10.1186/1471-2407-6-260. PMID 17076909. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.