TCEA1

From Wikipedia, the free encyclopedia

Transcription elongation factor A (SII), 1

PDB rendering based on 1tfi.

Available structures: 1tfi

Identifiers

Symbol(s)

TCEA1; GTF2S; SII; TCEA; TF2S; TFIIS

External IDs

OMIM: 601425 MGI: 1196624 HomoloGene: 55984

Gene ontology
Molecular Function:	• DNA binding • translation elongation factor activity • protein binding • zinc ion binding • general RNA polymerase II transcription factor activity • metal ion binding
Cellular Component:	• nucleus • nucleoplasm
Biological Process:	• RNA elongation • erythrocyte differentiation • positive regulation of transcription from RNA polymerase II promoter

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

XM_001127192 (mRNA)
XP_001127192 (protein)

NM_011541 (mRNA)
NP_035671 (protein)

Location

Chr 3: 37.29 - 37.29 Mb

Chr 15: 90.71 - 90.71 Mb

Pubmed search

[1]

[2]

Transcription elongation factor A (SII), 1, also known as TCEA1, is a human gene.^[1]

[edit] References

^ Entrez Gene: TCEA1 transcription elongation factor A (SII), 1.

[edit] Further reading

Chen HC, England L, Kane CM (1992). "Characterization of a HeLa cDNA clone encoding the human SII protein, an elongation factor for RNA polymerase II.". Gene 116 (2): 253–8. PMID 1378807.
Kato H, Sumimoto H, Pognonec P, et al. (1992). "HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors.". Genes Dev. 6 (4): 655–66. PMID 1559613.
Yoo OJ, Yoon HS, Baek KH, et al. (1991). "Cloning, expression and characterization of the human transcription elongation factor, TFIIS.". Nucleic Acids Res. 19 (5): 1073–9. PMID 1708494.
Reines D, Chamberlin MJ, Kane CM (1989). "Transcription elongation factor SII (TFIIS) enables RNA polymerase II to elongate through a block to transcription in a human gene in vitro.". J. Biol. Chem. 264 (18): 10799–809. PMID 2471707.
Qian X, Jeon C, Yoon H, et al. (1993). "Structure of a new nucleic-acid-binding motif in eukaryotic transcriptional elongation factor TFIIS.". Nature 365 (6443): 277–9. doi:10.1038/365277a0. PMID 7626141.
Park H, Baek K, Jeon C, et al. (1994). "Characterization of the gene encoding the human transcriptional elongation factor TFIIS.". Gene 139 (2): 263–7. PMID 8112616.
Yeh CH, Shatkin AJ (1994). "A HeLa-cell-encoded p21 is homologous to transcription elongation factor SII.". Gene 143 (2): 285–7. PMID 8206389.
Umehara T, Kida S, Yamamoto T, Horikoshi M (1996). "Isolation and characterization of a cDNA encoding a new type of human transcription elongation factor S-II.". Gene 167 (1-2): 297–302. PMID 8566795.
Powell W, Bartholomew B, Reines D (1996). "Elongation factor SII contacts the 3'-end of RNA in the RNA polymerase II elongation complex.". J. Biol. Chem. 271 (37): 22301–4. PMID 8798387.
DiMarco SP, Glover TW, Miller DE, et al. (1997). "Transcription elongation factor SII (TCEA) maps to human chromosome 3p22 --> p21.3.". Genomics 36 (1): 185–8. doi:10.1006/geno.1996.0443. PMID 8812434.
Pan G, Aso T, Greenblatt J (1997). "Interaction of elongation factors TFIIS and elongin A with a human RNA polymerase II holoenzyme capable of promoter-specific initiation and responsive to transcriptional activators.". J. Biol. Chem. 272 (39): 24563–71. PMID 9305922.
Li XY, Green MR (1998). "The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor.". Genes Dev. 12 (19): 2992–6. PMID 9765201.
Archambault J, Pan G, Dahmus GK, et al. (1998). "FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO.". J. Biol. Chem. 273 (42): 27593–601. PMID 9765293.
Suzuki H, Fukunishi Y, Kagawa I, et al. (2001). "Protein-protein interaction panel using mouse full-length cDNAs.". Genome Res. 11 (10): 1758–65. doi:10.1101/gr.180101. PMID 11591653.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Saso K, Ito T, Natori S, Sekimizu K (2004). "Identification of a novel tissue-specific transcriptional activator FESTA as a protein that interacts with the transcription elongation factor S-II.". J. Biochem. 133 (4): 493–500. PMID 12761297.
Imabayashi H, Mori T, Gojo S, et al. (2003). "Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis.". Exp. Cell Res. 288 (1): 35–50. PMID 12878157.
Kettenberger H, Armache KJ, Cramer P (2003). "Architecture of the RNA polymerase II-TFIIS complex and implications for mRNA cleavage.". Cell 114 (3): 347–57. PMID 12914699.
Tamura K, Miyata K, Sugahara K, et al. (2003). "Identification of EloA-BP1, a novel Elongin A binding protein with an exonuclease homology domain.". Biochem. Biophys. Res. Commun. 309 (1): 189–95. PMID 12943681.
Zhang C, Yan H, Burton ZF (2004). "Combinatorial control of human RNA polymerase II (RNAP II) pausing and transcript cleavage by transcription factor IIF, hepatitis delta antigen, and stimulatory factor II.". J. Biol. Chem. 278 (50): 50101–11. doi:10.1074/jbc.M307590200. PMID 14506279.