Tazobactam
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Tazobactam
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Systematic (IUPAC) name | |
(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-
(triazol-1-ylmethyl)-4$l^{6}-thia-1-azabicyclo[3.2.0] heptane-2-carboxylic acid |
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Identifiers | |
CAS number | |
ATC code | J01 |
PubChem | ? |
DrugBank | |
Chemical data | |
Formula | C10H12N4O5S |
Mol. mass | 300.289 g/mol |
Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
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Legal status | |
Routes | ? |
Tazobactam is a compound which inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin to produce Tazocin or Zosyn. It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.
Tazobactam sodium is a derivative of the penicillin nucleus and is a penicillanic acid sulfone.
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