Taurine-2-oxoglutarate transaminase

From Wikipedia, the free encyclopedia

In enzymology, a taurine-2-oxoglutarate transaminase (EC 2.6.1.55) is an enzyme that catalyzes the chemical reaction

taurine + 2-oxoglutarate sulfoacetaldehyde + L-glutamate

Thus, the two substrates of this enzyme are taurine and 2-oxoglutarate, whereas its two products are sulfoacetaldehyde and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is taurine:2-oxoglutarate aminotransferase. Other names in common use include taurine aminotransferase, taurine transaminase, taurine-alpha-ketoglutarate aminotransferase, and taurine-glutamate transaminase. This enzyme participates in beta-alanine metabolism. It employs one cofactor, pyridoxal phosphate.

[edit] References

• IUBMB entry for 2.6.1.55
• BRENDA references for 2.6.1.55 (Recommended.)
• PubMed references for 2.6.1.55
• PubMed Central references for 2.6.1.55
• Google Scholar references for 2.6.1.55
• Toyama S, Misono H, Soda K (1972). "Crystalline taurine: -ketoglutarate aminotransferase from Achromobacter superficialis". Biochem. Biophys. Res. Commun. 46: 1374–9. doi:10.1016/S0006-291X(72)80127-X. PMID 5012173. 
• Cook AM, Denger K (2002). "Dissimilation of the C2 sulfonates". Arch. Microbiol. 179: 1–6. doi:10.1007/s00203-002-0497-0. PMID 12471498. 

[edit] External links

The CAS registry number for this enzyme class is 9076-52-2.

• IUBMB entry for 2.6.1.55

• KEGG entry for 2.6.1.55

• BRENDA entry for 2.6.1.55

• NiceZyme view of 2.6.1.55

• EC2PDB: PDB structures for 2.6.1.55

• PRIAM entry for 2.6.1.55

• PUMA2 entry for 2.6.1.55

• IntEnz: Integrated Enzyme entry for 2.6.1.55

• MetaCyc entry for 2.6.1.55

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050322: taurine-2-oxoglutarate transaminase

• AMIGO entry for GO code 0050322: taurine-2-oxoglutarate transaminase