Tartrate dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a tartrate dehydrogenase (EC 1.1.1.93) is an enzyme that catalyzes the chemical reaction

tartrate + NAD⁺ oxaloglycolate + NADH + H⁺

Thus, the two substrates of this enzyme are tartrate and NAD⁺, whereas its 3 products are oxaloglycolate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is tartrate:NAD+ oxidoreductase. This enzyme is also called mesotartrate dehydrogenase. This enzyme participates in glyoxylate and dicarboxylate metabolism. It employs one cofactor, manganese.

[edit] References

• IUBMB entry for 1.1.1.93
• BRENDA references for 1.1.1.93 (Recommended.)
• PubMed references for 1.1.1.93
• PubMed Central references for 1.1.1.93
• Google Scholar references for 1.1.1.93
• Kohn LD, Packman PM, Allen RH, Jakoby WB (1968). "Tartaric acid metabolism. V. Crystalline tartrate dehydrogenase". J. Biol. Chem. 243: 2479–85. PMID 4297261. 

[edit] External links

The CAS registry number for this enzyme class is 37250-29-6.

• IUBMB entry for 1.1.1.93

• KEGG entry for 1.1.1.93

• BRENDA entry for 1.1.1.93

• NiceZyme view of 1.1.1.93

• EC2PDB: PDB structures for 1.1.1.93

• PRIAM entry for 1.1.1.93

• PUMA2 entry for 1.1.1.93

• IntEnz: Integrated Enzyme entry for 1.1.1.93

• MetaCyc entry for 1.1.1.93

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0009027: tartrate dehydrogenase

• AMIGO entry for GO code 0009027: tartrate dehydrogenase