TAOK3

From Wikipedia, the free encyclopedia

TAO kinase 3

Identifiers

TAOK3; DPK; DKFZp666H245; FLJ31808; JIK; MAP3K18

External IDs

Gene ontology
Molecular Function:	• nucleotide binding • protein serine/threonine kinase activity • protein kinase inhibitor activity • ATP binding • transferase activity
Biological Process:	• JNK cascade • negative regulation of JNK cascade • positive regulation of JNK cascade • protein amino acid autophosphorylation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_016281 (mRNA)
NP_057365 (protein)

XM_889805 (mRNA)
XP_894898 (protein)

Location

Chr 12: 117.07 - 117.3 Mb

Chr 5: 117.38 - 117.53 Mb

Pubmed search

[1]

[2]

TAO kinase 3, also known as TAOK3, is a human gene.^[1]

[edit] References

^ Entrez Gene: TAOK3 TAO kinase 3.

[edit] Further reading

Tassi E, Biesova Z, Di Fiore PP, et al. (1999). "Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factor.". J. Biol. Chem. 274 (47): 33287-95. PMID 10559204.
Zhang W, Chen T, Wan T, et al. (2000). "Cloning of DPK, a novel dendritic cell-derived protein kinase activating the ERK1/ERK2 and JNK/SAPK pathways.". Biochem. Biophys. Res. Commun. 274 (3): 872-9. doi:10.1006/bbrc.2000.3244. PMID 10924369.
Yoneda T, Imaizumi K, Oono K, et al. (2001). "Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress.". J. Biol. Chem. 276 (17): 13935-40. doi:10.1074/jbc.M010677200. PMID 11278723.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Yustein JT, Xia L, Kahlenburg JM, et al. (2003). "Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38.". Oncogene 22 (40): 6129-41. doi:10.1038/sj.onc.1206605. PMID 13679851.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Hartmann TB, Thiel D, Dummer R, et al. (2004). "SEREX identification of new tumour-associated antigens in cutaneous T-cell lymphoma.". Br. J. Dermatol. 150 (2): 252-8. PMID 14996095.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560.