SYT5

From Wikipedia, the free encyclopedia

Synaptotagmin V

Identifiers

External IDs

OMIM: 600782 MGI: 1926368 HomoloGene: 55722

Gene ontology
Molecular Function:	• transporter activity • calcium ion binding
Cellular Component:	• synaptic vesicle • membrane • integral to membrane • neuron projection • cell soma • synapse • perinuclear region of cytoplasm
Biological Process:	• transport • synaptic transmission

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003180 (mRNA)
NP_003171 (protein)

NM_016908 (mRNA)
NP_058604 (protein)

Location

Chr 19: 60.38 - 60.38 Mb

Chr 7: 4.14 - 4.15 Mb

Pubmed search

[1]

[2]

Synaptotagmin V, also known as SYT5, is a human gene.^[1]

[edit] References

^ Entrez Gene: SYT5 synaptotagmin V.

[edit] Further reading

Hudson AW, Birnbaum MJ (1995). "Identification of a nonneuronal isoform of synaptotagmin.". Proc. Natl. Acad. Sci. U.S.A. 92 (13): 5895-9. PMID 7597049.
Perin MS (1996). "Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin.". Biochemistry 35 (43): 13808-16. doi:10.1021/bi960853x. PMID 8901523.
Craxton M, Olsen A, Goedert M (1997). "Human synaptotagmin V (SYT5): sequence, genomic structure, and chromosomal location.". Genomics 42 (1): 165-9. doi:10.1006/geno.1997.4722. PMID 9177789.
Fukuda M, Kanno E, Mikoshiba K (1999). "Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.". J. Biol. Chem. 274 (44): 31421-7. PMID 10531343.
Craxton M, Goedert M (1999). "Alternative splicing of synaptotagmins involving transmembrane exon skipping.". FEBS Lett. 460 (3): 417-22. PMID 10556508.
Mizutani A, Fukuda M, Ibata K, et al. (2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms.". J. Biol. Chem. 275 (13): 9823-31. PMID 10734137.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Sreenath AS, Kumar KR, Reddy GV, et al. (2005). "Evidence for the association of synaptotagmin with glutathione S-transferases: implications for a novel function in human breast cancer.". Clin. Biochem. 38 (5): 436-43. doi:10.1016/j.clinbiochem.2005.01.009. PMID 15820774.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560.